The argument does not rest on an isolated claim. The underlying physics is compartment syndrome: any vascular bed confined within a rigid bony space collapses at pressures as low as 20-30 mmHg, regardless of the direction the compression comes from. In 1988, Perren et al. confirmed that this principle holds true in real bone: bone fixation by external compression induced measurable cortical necrosis, not a simple stress-protection response (Clin Orthop Relat Res 232:139–151) — the first direct proof that compressing cortical bone, in practice, does compromise its vascularization. The finding was independently confirmed by Uhthoff et al. in 1994 (J Bone Joint Surg 76-A:1507–1512). That same year, 1988, Brumback et al. consolidated a different engineering solution to the same problem: the statically locked intramedullary nail (J Bone Joint Surg 70:1453–1462), which anchors via a transverse canal crossed by a screw against the opposite cortex, without relying on sustained compression. RAMAX® applies that same physical principle — already demonstrated in real bone, and already solved with geometric anchorage in orthopedics for nearly four decades — to oral implantology; the GLP study with AnaPath does not aim to prove the general principle, but rather its translation to the scale of a dental implant.